In a piece on how slower than light space travel requires its own set of magic, Frank Landis writes:
Speaking of which, the crew: all astronauts, the best of the best, right? Good breeding stock and all? And their grandkids are going to settle the new planet? Well, erm, yeah. There are problems here too. One is that humans don’t breed true, so amazingly talented people tend to have less talented kids; it’s called regression to the mean. In a multigenerational setting, you have to allow for incredibly talented initial crew getting old, becoming incompetent, and passing off their responsibilities to their less-talented offspring. That’s tricky.
That seems like an excellent story premise.